Gene:  APOBEC3A, Human

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This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines which leads to DNA degradation. However other mechanisms are also thought to be involved as anti-viral effect is not dependent on deaminase activity. One allele of this gene results from the deletion of approximately 29.5 kb of sequence between this gene APOBEC3A and the adjacent gene APOBEC3B. The breakpoints of the deletion are within the two genes so the deletion allele is predicted to have the promoter and coding region of APOBEC3A but the 3' UTR of APOBEC3B. [provided by RefSeq Jul 2010]

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PrimePCR™ SYBR® Green Assay: APOBEC3A, Human
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038022
Info:   Same primer pair as used in probe assay qHsaCEP0040745
List Price:    $130.00
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PrimePCR™ Probe Assay: APOBEC3A, Human
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040745
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APOBEC3A, Human
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5188701
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038022; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: APOBEC3A, Human
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191093
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040745; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: APOBEC3A, Human
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191094
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040745; exonic
 
Fluorophore:   HEX
List Price:    $195.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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