Gene:  SEMA6D, Human

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Semaphorins are a large family including both secreted and membrane associated proteins many of which have been implicated as inhibitors or chemorepellents in axon pathfinding fasciculation and branching and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins like the secreted ones can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq Nov 2010]

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PrimePCR™ SYBR® Green Assay: SEMA6D, Human
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002872
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: SEMA6D, Human
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044792
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052054
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: SEMA6D, Human
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052054
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SEMA6D, Human
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5001486
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002872; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SEMA6D, Human
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5009409
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0044792; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SEMA6D, Human
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037130
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052054; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SEMA6D, Human
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037131
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052054; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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