Gene:  REN, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Design and Validation of Real-Time PCR Primers
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Control and Reference Assays for Real-Time PCR

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone releasevasoconstriction and increase in blood pressure. Renin an aspartyl protease cleaves angiotensinogen to form angiotensin I which is converted to angiotensin II by angiotensin I converting enzyme an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: REN, Human
renin

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045164
Info:   Same primer pair as used in probe assay qHsaCEP0052425
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PrimePCR™ SYBR® Green Assay: REN, Human
renin

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011493
Info:   Recommended - best coverage
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PrimePCR™ Probe Assay: REN, Human
renin

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052425
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PrimePCR™ ddPCR™ Copy Number Assay: REN, Human
renin

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000118
Info:   67nt amplicon; exonic
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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