Gene:  NOS1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene belongs to the family of nitric oxide synthases which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes including neurotransmission and antimicrobial and antitumoral activities. In the brain and peripheral nervous system nitric oxide displays many properties of a neurotransmitter and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases neural regulation of smooth muscle including peristalsis and penile erection. This protein is ubiquitously expressed with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq Feb 2011]

PrimePCR™ SYBR® Green Assay: NOS1, Human
nitric oxide synthase 1 (neuronal)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009103
Info:   Same primer pair as used in probe assay qHsaCIP0027049
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PrimePCR™ Probe Assay: NOS1, Human
nitric oxide synthase 1 (neuronal)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027049
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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