Gene:  GCLC, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Glutamate-cysteine ligase also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq Oct 2010]

PrimePCR™ SYBR® Green Assay: GCLC, Human
glutamate-cysteine ligase, catalytic subunit

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0038628
Info:   Same primer pair as used in probe assay qHsaCIP0041350
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PrimePCR™ Probe Assay: GCLC, Human
glutamate-cysteine ligase, catalytic subunit

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0041350
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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