Gene:  DAB2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C-terminal proline-rich sequences and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2011]

PrimePCR™ SYBR® Green Assay: DAB2, Human
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045591
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052852
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PrimePCR™ SYBR® Green Assay: DAB2, Human
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013898
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PrimePCR™ Probe Assay: DAB2, Human
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052852
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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