Gene:  CYP2D6, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine an adrenergic-blocking drug; sparteine and propafenone both anti-arrythmic drugs; and amitryptiline an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: CYP2D6, Human
cytochrome P450, family 2, subfamily D, polypeptide 6

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038655
Info:   Same primer pair as used in probe assay qHsaCEP0041377
List Price:    $130.00
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PrimePCR™ Probe Assay: CYP2D6, Human
cytochrome P450, family 2, subfamily D, polypeptide 6

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0041377
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CYP2D6, Human
cytochrome P450, family 2, subfamily D, polypeptide 6

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5188921
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038655; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Copy Number Assay: CYP2D6, Human
cytochrome P450, family 2, subfamily D, polypeptide 6

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506740
Info:   FAM; 107nt amplicon; exonic; FAM version of CYP2D6 (dHsaCP2506741)
 
Fluorophore:   FAM
List Price:    $240.00
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PrimePCR™ ddPCR™ Copy Number Assay: CYP2D6, Human
cytochrome P450, family 2, subfamily D, polypeptide 6

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506741
Info:   HEX; 107nt amplicon; exonic; HEX version of CYP2D6 (dHsaCP2506740)
 
Fluorophore:   HEX
List Price:    $240.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CYP2D6, Human
cytochrome P450, family 2, subfamily D, polypeptide 6

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191533
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041377; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CYP2D6, Human
cytochrome P450, family 2, subfamily D, polypeptide 6

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191534
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0041377; exonic
 
Fluorophore:   HEX
List Price:    $195.00
Your Price:   Log In
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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