Gene:  CTNNB1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally this protein binds to the product of the APC gene which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC) pilomatrixoma (PTR) medulloblastoma (MDB) and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq Oct 2009]

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PrimePCR™ SYBR® Green Assay: CTNNB1, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046518
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0053779
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PrimePCR™ SYBR® Green Assay: CTNNB1, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010363
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PrimePCR™ Probe Assay: CTNNB1, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053779
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PrimePCR™ ddPCR™ Copy Number Assay: CTNNB1, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000333
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 p.D32Y, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000091
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 WT for p.D32Y, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000092
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 p.G34E, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000097
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 WT for p.G34E, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000098
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 p.S37F, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000111
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 WT for p.S37F, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000112
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 p.S37C, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000115
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 WT for p.S37C, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000116
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 p.S45F, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000117
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 WT for p.S45F, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000118
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 p.S33C, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000119
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay: CTNNB1 WT for p.S33C, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000120
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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