Gene:  CTLA4, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain a transmembrane domain and a cytoplasmic tail. Alternate transcriptional splice variants encoding different isoforms have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus Graves disease Hashimoto thyroiditis celiac disease systemic lupus erythematosus thyroid-associated orbitopathy and other autoimmune diseases. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CTLA4, Human
cytotoxic T-lymphocyte-associated protein 4

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003794
Info:   Same primer pair as used in probe assay qHsaCEP0024830
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PrimePCR™ Probe Assay: CTLA4, Human
cytotoxic T-lymphocyte-associated protein 4

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024830
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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