Gene:  CKMT1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes sarcomeric MtCK and ubiquitous MtCK encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: CKMT1A, Human
creatine kinase, mitochondrial 1A

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038399
Info:   Same primer pair as used in probe assay qHsaCEP0041121
List Price:    $125.00
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PrimePCR™ Probe Assay: CKMT1A, Human
creatine kinase, mitochondrial 1A

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0041121
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CKMT1A, Human
creatine kinase, mitochondrial 1A

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5188863
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038399; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CKMT1A, Human
creatine kinase, mitochondrial 1A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191417
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041121; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CKMT1A, Human
creatine kinase, mitochondrial 1A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191418
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0041121; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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