Gene:  AVPR2, Human

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This gene encodes the vasopressin receptor type 2 also known as the V2 receptor which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor the V1a and V1b vasopressin receptors the oxytocin receptor and isotocin and mesotocin receptors in non-mammals is well conserved though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule predominantly in the distal convoluted tubule and collecting ducts where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP) a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: AVPR2, Human
arginine vasopressin receptor 2

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003845
List Price:    $130.00
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PrimePCR™ SYBR® Green Assay: AVPR2, Human
arginine vasopressin receptor 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044164
Info:   Same primer pair as used in probe assay qHsaCEP0051426
List Price:    $130.00
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Add to Custom Plate
PrimePCR™ Probe Assay: AVPR2, Human
arginine vasopressin receptor 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051426
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: AVPR2, Human
arginine vasopressin receptor 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5002210
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003845; Exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: AVPR2, Human
arginine vasopressin receptor 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5008850
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0044164; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: AVPR2, Human
arginine vasopressin receptor 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5036012
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051426; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: AVPR2, Human
arginine vasopressin receptor 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5036013
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051426; exonic
 
Fluorophore:   HEX
List Price:    $195.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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