Gene:  ANPEP, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Aminopeptidase N is located in the small-intestinal and renal microvillar membrane and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types including small intestinal and renal tubular epithelial cells macrophages granulocytes and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ANPEP, Human
alanyl (membrane) aminopeptidase

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046408
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0053669
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PrimePCR™ SYBR® Green Assay: ANPEP, Human
alanyl (membrane) aminopeptidase

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0015721
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PrimePCR™ Probe Assay: ANPEP, Human
alanyl (membrane) aminopeptidase

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053669
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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