Gene:  ALK, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a receptor tyrosine kinase which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain an hydrophobic stretch corresponding to a single pass transmembrane region and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged mutated or amplified in a series of tumours including anaplastic large cell lymphomas neuroblastoma and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene which result in creation of multiple fusion genes in tumourigenesis including ALK (chromosome 2)/EML4 (chromosome 2) ALK/RANBP2 (chromosome 2) ALK/ATIC (chromosome 2) ALK/TFG (chromosome 3) ALK/NPM1 (chromosome 5) ALK/SQSTM1 (chromosome 5) ALK/KIF5B (chromosome 10) ALK/CLTC (chromosome 17) ALK/TPM4 (chromosome 19) and ALK/MSN (chromosome X).[provided by RefSeq Jan 2011]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0004126
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046769
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0054030
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054030
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5002438
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0004126; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5011179
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046769; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Copy Number Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000588
Info:   FAM; 64nt amplicon; exonic; FAM version of ALK (dHsaCP2506492)
 
Fluorophore:   FAM
List Price:    $230.00
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PrimePCR™ ddPCR™ Mutation Assay: ALK p.G1269A, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000081
Info:   64nt amplicon; crosses exon-intron junction
 
Fluorophore:   FAM
List Price:    $380.00
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PrimePCR™ ddPCR™ Mutation Assay: ALK WT for p.G1269A, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000082
Info:   64nt amplicon; crosses exon-intron junction
 
Fluorophore:   HEX
List Price:    $380.00
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PrimePCR™ ddPCR™ Mutation Assay: ALK p.F1174L, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000083
Info:   65nt amplicon; crosses exon-intron junction
 
Fluorophore:   FAM
List Price:    $380.00
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PrimePCR™ ddPCR™ Mutation Assay: ALK WT for p.F1174L, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000084
Info:   65nt amplicon; crosses exon-intron junction
 
Fluorophore:   HEX
List Price:    $380.00
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PrimePCR™ ddPCR™ Copy Number Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506492
Info:   HEX; 64nt amplicon; exonic; HEX version of ALK (dHsaCP1000588)
 
Fluorophore:   HEX
List Price:    $230.00
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PrimePCR™ ddPCR™ Mutation Assay: ALK p.R1275Q, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506768
Info:   64nt amplicon; crosses exon-intron junction
 
Fluorophore:   FAM
List Price:    $380.00
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PrimePCR™ ddPCR™ Mutation Assay: ALK WT for p.R1275Q, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506769
Info:   64nt amplicon; crosses exon-intron junction
 
Fluorophore:   HEX
List Price:    $380.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5040668
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054030; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ALK, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5040669
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054030; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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PrimePCR™ ddPCR™ Mutation Assay:ALK p.F1174L, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501840
Info:   65nt amplicon; crosses exon-intron junction; in silico
 
Fluorophore:   FAM
List Price:    $315.00
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PrimePCR™ ddPCR™ Mutation Assay:ALK WT for p.F1174L, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501841
Info:   65nt amplicon; crosses exon-intron junction; in silico
 
Fluorophore:   HEX
List Price:    $315.00
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PrimePCR™ ddPCR™ Mutation Assay:ALK p.F1174V, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504636
Info:   65nt amplicon; crosses exon-intron junction; in silico
 
Fluorophore:   FAM
List Price:    $315.00
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PrimePCR™ ddPCR™ Mutation Assay:ALK WT for p.F1174V, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504637
Info:   65nt amplicon; crosses exon-intron junction; in silico
 
Fluorophore:   HEX
List Price:    $315.00
Your Price:   Log In
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PrimePCR™ ddPCR™ Mutation Assay:ALK p.F1174L, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2505978
Info:   65nt amplicon; crosses exon-intron junction; in silico
 
Fluorophore:   FAM
List Price:    $315.00
Your Price:   Log In
Quantity:  
 
PrimePCR™ ddPCR™ Mutation Assay:ALK WT for p.F1174L, Human
anaplastic lymphoma receptor tyrosine kinase

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2505979
Info:   65nt amplicon; crosses exon-intron junction; in silico
 
Fluorophore:   HEX
List Price:    $315.00
Your Price:   Log In
Quantity:  
 
    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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