Gene:  XIAP, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed baculovirus IAP repeat which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione a potent inducer of free radicals and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq Feb 2011]

PrimePCR™ SYBR® Green Assay: XIAP, Human
X-linked inhibitor of apoptosis

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037909
Info:   Same primer pair as used in probe assay qHsaCEP0040632
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PrimePCR™ Probe Assay: XIAP, Human
X-linked inhibitor of apoptosis

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040632
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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