Gene:  WNT1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member WNT10B in the chromosome 12q13 region. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: WNT1, Human
wingless-type MMTV integration site family, member 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014659
Info:   Same primer pair as used in probe assay qHsaCIP0029498
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PrimePCR™ Probe Assay: WNT1, Human
wingless-type MMTV integration site family, member 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029498
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