Gene:  UCP2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: UCP2, Human
uncoupling protein 2 (mitochondrial, proton carrier)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013753
Info:   Same primer pair as used in probe assay qHsaCIP0029025
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PrimePCR™ Probe Assay: UCP2, Human
uncoupling protein 2 (mitochondrial, proton carrier)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029025
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