Gene:  Trp73, Mouse

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This gene encodes tumor protein p73 which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53 p63 and p73 and have high sequence similarity to one another which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters alternate translation initiation sites and multiple splice variations. Theoretically this can account for 29 different p73 isoforms; however the biological validity and the full-length nature of most variants have not been determined. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: Trp73, Mouse
Transformation related protein 73

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCED0048073
Info:   Recommended - best coverage; Same primer pair as used in probe assay qMmuCEP0056499
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PrimePCR™ SYBR® Green Assay: Trp73, Mouse
Transformation related protein 73

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qMmuCID0006017
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PrimePCR™ Probe Assay: Trp73, Mouse
Transformation related protein 73

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCEP0056499
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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