Gene:  TIRAP, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs) which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B MAPK1 MAPK3 and JNK which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however not all variants have been fully described. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: TIRAP, Human
toll-interleukin 1 receptor (TIR) domain containing adaptor protein

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0034776
Info:   Same primer pair as used in probe assay qHsaCEP0035601
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PrimePCR™ Probe Assay: TIRAP, Human
toll-interleukin 1 receptor (TIR) domain containing adaptor protein

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0035601
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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