Gene:  TIMP1, Human

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This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs) a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs the encoded protein is able to promote cell proliferation in a wide range of cell types and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: TIMP1, Human
TIMP metallopeptidase inhibitor 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042919
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0050181
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PrimePCR™ SYBR® Green Assay: TIMP1, Human
TIMP metallopeptidase inhibitor 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0007434
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PrimePCR™ Probe Assay: TIMP1, Human
TIMP metallopeptidase inhibitor 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050181
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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