Gene:  TCL1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al. 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al. 2000 [PubMed 10983986]).[supplied by OMIM Jul 2010]

PrimePCR™ SYBR® Green Assay: TCL1A, Human
T-cell leukemia/lymphoma 1A

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0033928
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PrimePCR™ SYBR® Green Assay: TCL1A, Human
T-cell leukemia/lymphoma 1A

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042816
Info:   Same primer pair as used in probe assay qHsaCEP0050078
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PrimePCR™ Probe Assay: TCL1A, Human
T-cell leukemia/lymphoma 1A

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050078
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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