Gene:  STAT5A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by and mediates the responses of many cell ligands such as IL2 IL3 IL7 GM-CSF erythropoietin thrombopoietin and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L) which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: STAT5A, Human
signal transducer and activator of transcription 5A

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002322
Info:   Same primer pair as used in probe assay qHsaCEP0024348
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PrimePCR™ Probe Assay: STAT5A, Human
signal transducer and activator of transcription 5A

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024348
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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