Gene:  SPTA1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape arrangement of transmembrane proteins and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders including elliptocytosis type 2 pyropoikilocytosis and spherocytic hemolytic anemia. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: SPTA1, Human
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014690
Info:   Same primer pair as used in probe assay qHsaCIP0029512
List Price:    $174.00
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PrimePCR™ Probe Assay: SPTA1, Human
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029512
List Price:    $255.00
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