Gene:  SORT1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein a trans-Golgi network (TGN) transmembrane protein binds a number of unrelated ligands that participate in a wide range of cellular processes; however it lacks the typical features of a signalling receptor. In the TGN furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated gamma-adaptin homologous ARF-interacting) proteins. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: SORT1, Human
sortilin 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014682
Info:   Same primer pair as used in probe assay qHsaCIP0029508
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PrimePCR™ Probe Assay: SORT1, Human
sortilin 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029508
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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