Gene:  SHANK2, Human

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This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction including ankyrin repeats an SH3 domain a PSD-95/Dlg/ZO-1 domain a sterile alpha motif domain and a proline-rich region. This particular family member contains a PDZ domain a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants encoding distinct isoforms are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: SHANK2, Human
SH3 and multiple ankyrin repeat domains 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021499
Info:   Same primer pair as used in probe assay qHsaCIP0033063
List Price:    $125.00
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PrimePCR™ Probe Assay: SHANK2, Human
SH3 and multiple ankyrin repeat domains 2

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0033063
List Price:    $355.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SHANK2, Human
SH3 and multiple ankyrin repeat domains 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5024010
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021499; Intron-spanning
List Price:    $120.00
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PrimePCR™ ddPCR™ Copy Number Assay: SHANK2, Human
SH3 and multiple ankyrin repeat domains 2

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2500304
Info:   FAM; 67nt amplicon; exonic; FAM version of SHANK2 (dHsaCP2506482)
 
Fluorophore:   FAM
List Price:    $220.00
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PrimePCR™ ddPCR™ Copy Number Assay: SHANK2, Human
SH3 and multiple ankyrin repeat domains 2

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506482
Info:   HEX; 67nt amplicon; exonic; HEX version of SHANK2 (dHsaCP2500304)
 
Fluorophore:   HEX
List Price:    $220.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SHANK2, Human
SH3 and multiple ankyrin repeat domains 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057524
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033063; Intron-spanning
 
Fluorophore:   FAM
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SHANK2, Human
SH3 and multiple ankyrin repeat domains 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057525
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0033063; Intron-spanning
 
Fluorophore:   HEX
List Price:    $180.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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