Gene:  Psen2, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch receptors and the amyloid precursor protein. The encoded protein contains eight transmembrane domains and is localized to the endoplasmic reticulum where it may play a role in calcium homeostasis. Following assembly of the gamma-secretase complex the encoded protein is cleaved into N- and C-terminal fragments and the activated complex is released from the endoplasmic reticulum. Inactivation of this gene results in impaired synaptic function in a mouse model for Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq Apr 2011]

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PrimePCR™ SYBR® Green Assay: Psen2, Rat
Presenilin-2 Presenilin-2 NTF subunit Presenilin-2 CTF subunit

Assay Type: SYBR® Green
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qRnoCID0002199
List Price:    $134.00
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PrimePCR™ Probe Assay: Psen2, Rat
Presenilin-2 Presenilin-2 NTF subunit Presenilin-2 CTF subunit

Assay Type: Probe
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qRnoCIP0024030
List Price:    $196.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Psen2, Rat
Presenilin-2 Presenilin-2 NTF subunit Presenilin-2 CTF subunit

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dRnoEG5136253
Info:   EG; Same primer pair as used in qPCR assay qRnoCID0002199; intron_spanning
List Price:    $134.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Psen2, Rat
Presenilin-2 Presenilin-2 NTF subunit Presenilin-2 CTF subunit

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dRnoCPE5168484
Info:   FAM; Same primer pair and probe as used in qPCR assay qRnoCIP0024030; intron_spanning
 
Fluorophore:   FAM
List Price:    $201.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Psen2, Rat
Presenilin-2 Presenilin-2 NTF subunit Presenilin-2 CTF subunit

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dRnoCPE5168485
Info:   HEX; Same primer pair and probe as used in qPCR assay qRnoCIP0024030; intron_spanning
 
Fluorophore:   HEX
List Price:    $201.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download