Gene:  PPM1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates and negatively regulates the activities of MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53 which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: PPM1A, Human
protein phosphatase, Mg2+/Mn2+ dependent, 1A

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0022142
Info:   Same primer pair as used in probe assay qHsaCIP0033308
List Price:    $130.00
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PrimePCR™ Probe Assay: PPM1A, Human
protein phosphatase, Mg2+/Mn2+ dependent, 1A

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0033308
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PPM1A, Human
protein phosphatase, Mg2+/Mn2+ dependent, 1A

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5024295
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0022142; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PPM1A, Human
protein phosphatase, Mg2+/Mn2+ dependent, 1A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057820
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033308; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PPM1A, Human
protein phosphatase, Mg2+/Mn2+ dependent, 1A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057821
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0033308; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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