Gene:  PPARGC1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma which permits the interaction of this protein with multiple transcription factors. This protein can interact with and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure regulating cellular cholesterol homoeostasis and the development of obesity. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: PPARGC1A, Human
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006418
Info:   Same primer pair as used in probe assay qHsaCIP0026151
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PrimePCR™ Probe Assay: PPARGC1A, Human
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026151
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PrimePCR™ ddPCR™ Mutation Assay:PPARGC1A p.S759P, Human
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2505690
Info:   79nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:PPARGC1A WT for p.S759P, Human
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2505691
Info:   79nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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