Gene:  PLAT, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes tissue-type plasminogen activator a secreted serine protease which converts the proenzyme plasminogen to plasmin a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: PLAT, Human
plasminogen activator, tissue

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012552
Info:   Same primer pair as used in probe assay qHsaCIP0028495
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PrimePCR™ Probe Assay: PLAT, Human
plasminogen activator, tissue

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028495
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PLAT, Human
plasminogen activator, tissue

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5018719
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012552; Intron-spanning
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PrimePCR™ ddPCR™ Expression Probe Assay: PLAT, Human
plasminogen activator, tissue

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5050796
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028495; Intron-spanning
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Expression Probe Assay: PLAT, Human
plasminogen activator, tissue

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5050797
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028495; Intron-spanning
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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