Gene:  PBX1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation t(1;19) involving this gene and TCF3/E2A gene is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Mar 2011]

PrimePCR™ SYBR® Green Assay: PBX1, Human
pre-B-cell leukemia homeobox 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001390
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PrimePCR™ SYBR® Green Assay: PBX1, Human
pre-B-cell leukemia homeobox 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047760
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0055020
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PrimePCR™ Probe Assay: PBX1, Human
pre-B-cell leukemia homeobox 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055020
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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