Gene:  NR1H3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs including liver kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR) and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2011]

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PrimePCR™ SYBR® Green Assay: NR1H3, Human
nuclear receptor subfamily 1, group H, member 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013633
Info:   Same primer pair as used in probe assay qHsaCIP0028960
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PrimePCR™ Probe Assay: NR1H3, Human
nuclear receptor subfamily 1, group H, member 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028960
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PrimePCR™ ddPCR™ Mutation Assay:NR1H3 p.R226W, Human
nuclear receptor subfamily 1, group H, member 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504694
Info:   65nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:NR1H3 WT for p.R226W, Human
nuclear receptor subfamily 1, group H, member 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504695
Info:   65nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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