Gene:  NPR1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Guanylyl cyclases catalyzing the production of cGMP from GTP are classified as soluble and membrane forms (Garbers and Lowe 1994 [PubMed 7982997]). The membrane guanylyl cyclases often termed guanylyl cyclases A through F form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain a single membrane-spanning domain and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962) which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295) respectively).[supplied by OMIM May 2009]

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PrimePCR™ SYBR® Green Assay: NPR1, Human
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046631
Info:   Same primer pair as used in probe assay qHsaCEP0053892
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: NPR1, Human
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013182
Info:   Recommended - best coverage
List Price:    $125.00
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PrimePCR™ Probe Assay: NPR1, Human
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053892
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NPR1, Human
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5011055
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046631; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NPR1, Human
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5019157
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013182; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: NPR1, Human
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5040420
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053892; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: NPR1, Human
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5040421
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053892; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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