Gene:  NLRP8, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs such as NALP8 have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD) followed by a NACHT domain a NACHT-associated domain (NAD) and a C-terminal leucine-rich repeat (LRR) region. The long NALP NALP1 (MIM 606636) also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g. CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al. 2003 [PubMed 12563287]).[supplied by OMIM Mar 2008]

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PrimePCR™ SYBR® Green Assay: NLRP8, Human
NLR family, pyrin domain containing 8

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0015774
Info:   Same primer pair as used in probe assay qHsaCIP0030155
List Price:    $125.00
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PrimePCR™ Probe Assay: NLRP8, Human
NLR family, pyrin domain containing 8

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030155
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NLRP8, Human
NLR family, pyrin domain containing 8

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5021106
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015774; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: NLRP8, Human
NLR family, pyrin domain containing 8

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5053636
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030155; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: NLRP8, Human
NLR family, pyrin domain containing 8

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5053637
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030155; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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