Gene:  MYD88, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq Feb 2010]

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PrimePCR™ SYBR® Green Assay: MYD88, Human
myeloid differentiation primary response gene (88)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0006915
Info:   Recommended - best coverage
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PrimePCR™ SYBR® Green Assay: MYD88, Human
myeloid differentiation primary response gene (88)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046947
Info:   Same primer pair as used in probe assay qHsaCEP0054208
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PrimePCR™ Probe Assay: MYD88, Human
myeloid differentiation primary response gene (88)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054208
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PrimePCR™ ddPCR™ Mutation Assay:MYD88 p.S219C, Human
myeloid differentiation primary response gene (88)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2500634
Info:   65nt amplicon; exonic; in-silico designed
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:MYD88 WT for p.S219C, Human
myeloid differentiation primary response gene (88)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2500635
Info:   65nt amplicon; exonic; in-silico designed
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay:MYD88 p.S243N, Human
myeloid differentiation primary response gene (88)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2501102
Info:   65nt amplicon; exonic; in-silico designed
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:MYD88 WT for p.S243N, Human
myeloid differentiation primary response gene (88)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2501103
Info:   65nt amplicon; exonic; in-silico designed
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay:MYD88 p.M232T, Human
myeloid differentiation primary response gene (88)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2505870
Info:   61nt amplicon; crosses exon-intron junction; in-silico designed
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:MYD88 WT for p.M232T, Human
myeloid differentiation primary response gene (88)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2505871
Info:   61nt amplicon; crosses exon-intron junction; in-silico designed
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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