Gene:  MLH3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Design and Validation of Real-Time PCR Primers
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This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified but the full-length nature of only two transcript variants has been determined. [provided by RefSeq Jul 2008]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: MLH3, Human
mutL homolog 3 (E. coli)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021156
Info:   Same primer pair as used in probe assay qHsaCIP0032937
List Price:    $125.00
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PrimePCR™ Probe Assay: MLH3, Human
mutL homolog 3 (E. coli)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0032937
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MLH3, Human
mutL homolog 3 (E. coli)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5023807
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021156; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: MLH3, Human
mutL homolog 3 (E. coli)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057340
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0032937; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: MLH3, Human
mutL homolog 3 (E. coli)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057341
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0032937; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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