Gene:  MAPK9, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development. This kinase targets specific transcription factors and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8 both of which are involved in UV radiation induced apoptosis thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53 and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Sep 2008]

PrimePCR™ SYBR® Green Assay: MAPK9, Human
mitogen-activated protein kinase 9

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0036311
Info:   Same primer pair as used in probe assay qHsaCIP0039035
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PrimePCR™ Probe Assay: MAPK9, Human
mitogen-activated protein kinase 9

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0039035
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