Gene:  IL10, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines MHC class II Ags and costimulatory molecules on macrophages. It also enhances B cell survival proliferation and antibody production. This cytokine can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq May 2011]

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PrimePCR™ SYBR® Green Assay: IL10, Human
interleukin 10

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003369
Info:   Recommended - best efficiency
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PrimePCR™ SYBR® Green Assay: IL10, Human
interleukin 10

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044704
Info:   Same primer pair as used in probe assay qHsaCEP0051966
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PrimePCR™ Probe Assay: IL10, Human
interleukin 10

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051966
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PrimePCR™ ddPCR™ Copy Number Assay: IL10, Human
interleukin 10

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000209
Info:   76nt amplicon; intronic
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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