Gene:  GRN, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Granulins are a family of secreted glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein progranulin is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active 6 kDa peptides. These smaller cleavage products are named granulin A granulin B granulin C etc. Epithelins 1 and 2 are synonymous with granulins A and B respectively. Both the peptides and intact granulin protein regulate cell growth. However different members of the granulin protein family may act as inhibitors stimulators or have dual actions on cell growth. Granulin family members are important in normal development wound healing and tumorigenesis. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: GRN, Human
granulin

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003622
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PrimePCR™ SYBR® Green Assay: GRN, Human
granulin

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0056716
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0057821
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PrimePCR™ Probe Assay: GRN, Human
granulin

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0057821
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PrimePCR™ ddPCR™ Copy Number Assay: GRN, Human
granulin

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000380
Info:   63nt amplicon; intronic
 
Fluorophore:   FAM
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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