Gene:  FKBP1A, Human

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The protein encoded by this gene is a member of the immunophilin protein family which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants encoding the same protein have been identified. The human genome contains five pseudogenes related to this gene at least one of which is transcribed. [provided by RefSeq Sep 2008]

PrimePCR™ SYBR® Green Assay: FKBP1A, Human
FK506 binding protein 1A, 12kDa

Assay Type: SYBR® Green
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0038651
Info:   Same primer pair as used in probe assay qHsaCIP0041373
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PrimePCR™ Probe Assay: FKBP1A, Human
FK506 binding protein 1A, 12kDa

Assay Type: Probe
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0041373
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