Gene:  F7, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form and is converted to an active form by either factor IXa factor Xa factor XIIa or thrombin by minor proteolysis. Upon activation of the factor VII a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: F7, Human
coagulation factor VII (serum prothrombin conversion accelerator)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010400
Info:   Same primer pair as used in probe assay qHsaCIP0027569
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PrimePCR™ Probe Assay: F7, Human
coagulation factor VII (serum prothrombin conversion accelerator)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027569
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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