Gene:  ERCC2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders the cancer-prone syndrome xeroderma pigmentosum complementation group D trichothiodystrophy and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Aug 2008]

PrimePCR™ SYBR® Green Assay: ERCC2, Human
excision repair cross-complementing rodent repair deficiency, complementation group 2

Assay Type: SYBR® Green
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0037822
Info:   Same primer pair as used in probe assay qHsaCIP0040545
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PrimePCR™ Probe Assay: ERCC2, Human
excision repair cross-complementing rodent repair deficiency, complementation group 2

Assay Type: Probe
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0040545
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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