Gene:  DYNLL1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1200 kD. They contain two force-producing heads formed primarily from dynein heavy chains and stalks linking the heads to a basal domain which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer a conformation necessary for activity and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: DYNLL1, Human
dynein, light chain, LC8-type 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0023801
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PrimePCR™ SYBR® Green Assay: DYNLL1, Human
dynein, light chain, LC8-type 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0056818
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0057923
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PrimePCR™ Probe Assay: DYNLL1, Human
dynein, light chain, LC8-type 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0057923
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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