Gene:  CYP3A5, Human

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This geneCYP3A5 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene CYP3A5P1 which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq Jun 2010]

PrimePCR™ SYBR® Green Assay: CYP3A5, Human
cytochrome P450, family 3, subfamily A, polypeptide 5

Assay Type: SYBR® Green
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0036396
Info:   Same primer pair as used in probe assay qHsaCIP0039120
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PrimePCR™ Probe Assay: CYP3A5, Human
cytochrome P450, family 3, subfamily A, polypeptide 5

Assay Type: Probe
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0039120
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