Gene:  CREBL2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes frequently associated with hematopoietic malignancies as well as breast non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CREBL2, Chicken
Uncharacterized protein

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qGgaCED0026491
List Price:    $102.00
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PrimePCR™ Probe Assay: CREBL2, Chicken
Uncharacterized protein

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qGgaCEP0010957
List Price:    $196.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download