Gene:  CR1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes leukocytes glomerular podocytes and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas mesangiocapillary glomerulonephritis systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting conferring protection against severe malaria. Alternate allele-specific splice variants encoding different isoforms have been characterized. Additional allele specific isoforms including a secreted form have been described but have not been fully characterized. [provided by RefSeq Jul 2008]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0048412
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0055672
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013379
List Price:    $125.00
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PrimePCR™ Probe Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055672
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5012643
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048412; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5019288
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013379; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Copy Number Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000184
Info:   FAM: 68nt amplicon; exonic
 
Fluorophore:   FAM
List Price:    $230.00
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PrimePCR™ ddPCR™ Copy Number Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2507009
Info:   HEX; 68nt amplicon; exonic; HEX version of CR1 (dHsaCP1000184)
 
Fluorophore:   HEX
List Price:    $230.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043596
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055672; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CR1, Human
complement component (3b/4b) receptor 1 (Knops blood group)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043597
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055672; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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