Gene:  COL1A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone cornea dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV Ehlers-Danlos syndrome type VIIA Ehlers-Danlos syndrome Classical type Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22 where this gene and the gene for platelet-derived growth factor beta are located are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of the growth factor. Two transcripts resulting from the use of alternate polyadenylation signals have been identified for this gene. [provided by R. Dalgleish Feb 2008]

PrimePCR™ SYBR® Green Assay: COL1A1, Human
collagen, type I, alpha 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002181
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PrimePCR™ SYBR® Green Assay: COL1A1, Human
collagen, type I, alpha 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043248
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0050510
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PrimePCR™ Probe Assay: COL1A1, Human
collagen, type I, alpha 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050510
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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