Gene:  CHRNA4, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a nicotinic acetylcholine receptor which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq Feb 2012]

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PrimePCR™ SYBR® Green Assay: CHRNA4, Human
cholinergic receptor, nicotinic, alpha 4

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006845
Info:   Same primer pair as used in probe assay qHsaCIP0026313
List Price:    $130.00
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PrimePCR™ Probe Assay: CHRNA4, Human
cholinergic receptor, nicotinic, alpha 4

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026313
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHRNA4, Human
cholinergic receptor, nicotinic, alpha 4

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5014770
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0006845; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHRNA4, Human
cholinergic receptor, nicotinic, alpha 4

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047042
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026313; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHRNA4, Human
cholinergic receptor, nicotinic, alpha 4

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047043
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026313; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
Your Price:   Log In
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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