Gene:  CHEK1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR two cell cycle proteins involved in DNA damage responses that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Oct 2011]

PrimePCR™ SYBR® Green Assay: CHEK1, Human
CHK1 checkpoint homolog (S. pombe)

Assay Type: SYBR® Green
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0037755
Info:   Same primer pair as used in probe assay qHsaCIP0040478
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PrimePCR™ Probe Assay: CHEK1, Human
CHK1 checkpoint homolog (S. pombe)

Assay Type: Probe
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0040478
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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