Gene:  CDKN2B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor which forms a complex with CDK4 or CDK6 and prevents the activation of the CDK kinases thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene which encode distinct proteins have been reported. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: CDKN2B, Human
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0005596
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PrimePCR™ SYBR® Green Assay: CDKN2B, Human
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045392
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052653
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PrimePCR™ Probe Assay: CDKN2B, Human
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052653
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PrimePCR™ ddPCR™ Copy Number Assay: CDKN2B, Human
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000121
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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