Gene:  CCND1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene belongs to the highly conserved cyclin family whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6 whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations amplification and overexpression of this gene which alters cell cycle progression are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: CCND1, Human
cyclin D1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013833
Info:   Same primer pair as used in probe assay qHsaCIP0029062
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PrimePCR™ Probe Assay: CCND1, Human
cyclin D1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029062
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PrimePCR™ ddPCR™ Copy Number Assay: CCND1, Human
cyclin D1

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000010
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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