Gene:  CACNA1C, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1 alpha-2/delta beta and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: CACNA1C, Human
calcium channel, voltage-dependent, L type, alpha 1C subunit

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045498
Info:   Same primer pair as used in probe assay qHsaCEP0052759
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PrimePCR™ SYBR® Green Assay: CACNA1C, Human
calcium channel, voltage-dependent, L type, alpha 1C subunit

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011853
Info:   Recommended - best coverage
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PrimePCR™ Probe Assay: CACNA1C, Human
calcium channel, voltage-dependent, L type, alpha 1C subunit

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052759
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PrimePCR™ ddPCR™ Copy Number Assay: CACNA1C, Human
calcium channel, voltage-dependent, L type, alpha 1C subunit

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000563
Info:   66nt amplicon; exonic
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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